Sentence examples for mutation we detected from inspiring English sources

These results further pinpoint the mutation we detected at the hit locus as the single mutation associated with the HI phenotype in the HI mutant sequenced by NGS.

The frequency of p16 mutation we detected is higher than previously reported in EA or in BE found in surgical resections [11], [15], [30], [50] [53].

Besides the G12V HRAS mutation used in the transformation experiment to derive the premalignant cell line MCF10AT from MCF10A, the only mutation we detected was PIK3CA H1047R, which is known to be the most common activating mutation in the PIK3CA gene in human cancer [15], [16].

Eight strains contain the same zhf1 mutation (W324L) observed previously, making it the most common mutation we detected.

Although the EGFR exon 20 S768I mutation is considered to be a very rare mutation, we detected a total of 24 (0.5%) NSCLC harbouring this mutation.

Using two independent sensitive methods, respectively, based on SNaPshot and PCR-LCR assays specifically designed to detect KRAS mutation, we detected additional mutations in two patients with SD, four with PD but none in 11 with CR/PR.

In this study, we aimed to elucidate whether Bcl11b is mutated in lymphomas with allelic loss, and whether the mutations we detected conferred any effect on cell proliferation and apoptosis.

However, one of the mutations we detected, R304W, appeared to be associated with a high risk of breast cancer.

Finally, we observed that double mutants are no more fit than the best single mutant, suggesting that all the mutations we detected are addressing the same physiological limitation.

Irrespective of the low frequency of somatic mutations we detected in the tumor samples we found large aberrations in copy number.

Of 31 clinically relevant disease mutations, we detected all 31, for a sensitivity at disease-causing loci of 100%9595% CI: 88.8 100%).