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Exact(6)
We also demonstrated that this post-zygotic mutation was restricted to the monocytic lineage.
Thereafter, we observed that the somatic mosaicism of SQSTM1/P392L mutation was restricted to the monocytic lineage.
The LNA PCR-clamping method performed on DNA from monocytes, lymphocytes and saliva suggested that the post-zygotic mutation was restricted to the monocytic lineage.
The excess risk of prostate cancer attributable to a CHEK2 mutation was restricted to carriers of the VV genotype at p27.
Although we were unable to confirm the presence of the SQSTM1/P392L post-zygotic mutation in an affected bone, we observed that the presence of this mutation was restricted to monocytes, the osteoclasts precursors.
Berres et al. [ 102] reported that patients with LCH-RO carried the BRAF V600E mutation in circulating CD11c + and CD14+ cellular fractions as well as in BM CD34+ hematopoietic cell progenitors, whereas the mutation was restricted to lesional LCH cells in patients with LCH-RO.
Similar(54)
The nucleotide change at position 125 was present only in two WSSV isolates from India including the isolate reported in this paper indicating that this mutation is restricted to India.
Nonetheless, our results suggest that the publish-subscribe model holds remarkable evolutionary potential even when mutation is restricted to single steps.
To date it remains unknown whether the mutation is restricted to glial tumor cells.
The premature stop precore mutation is restricted to HBV genotypes containing a thymidine at nucleotide position 1858, which is required for stabilizing the stem loop structure (26 ).
Analysis of the DNA sequences for H3F3A and H3F3B illuminates why the K27M mutation is restricted to H3F3A, as K27 is coded by AAG in H3F3A and by AAA in H3F3B, requiring a single mutation in H3F3A to generate ATG to code for methionine (Fig. 3).
Related(20)
deployment was restricted
move was restricted
transformation was restricted
mutation was confined
transfer was restricted
mutation was small
mutation was described
mutation was detected
mutation was repeated
mutation was confirmed
mutation was labeled
mutation was genotyped
mutation was created
mutation was backcrossed
mutation was introduced
mutation was expected
mutation was termed
mutation was found
mutation was named
mutation was identified
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