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This latter mutation was confined to the tumor.
In our study, BRAF mutation was confined to PTC and was not detected in benign lesions.
To rule this out, we obtained a second allele, tm3223, where the mutation was confined to dnj-14 alone.
All but one mutation was confined within three distinct regions, suggesting that they might be under selective pressure.
However, one mutation was confined to intron 11; therefore the biologic significance of this mutation is unknown[ 11].
Positional cloning work, in which the position of the mutation was confined to a narrow chromosomal interval by classical mapping methods and all sequences within this interval were examined for mutations, revealed that the lesion altered the structure of a mammalian homolog of Toll – TLR4 [ 32].
Similar(54)
All but one mutation were confined within three distinct regions.
Hence, the prognostic value of the BRAF mutation is confined to the MSS/left-sided tumors.
In this study, the definition of a genetic mutation is confined to the protein-truncating mutation and the missense mutation, which have a confirmed association to disease.
Until recently, routine screening of tumours for mutations was confined to low- and medium-throughput platforms.
In all cases, mutations were confined to the targeted positions, and no spurious changes were detected.
More suggestions(15)
abnormality was confined
mutation was described
mutation was detected
mutation was labeled
mutation was repeated
mutation was confirmed
mutation was genotyped
mutation was created
mutation was backcrossed
mutation was introduced
mutation was expected
mutation was termed
mutation was found
mutation was named
mutation were confined
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