Sentence examples for mutation was created from inspiring English sources

The E675A catalytic mutation was created by mutating codon 675 gAa to gCa in pch cloned into pUC18Tmini-Tn7T.

To determine the importance of this divergent region, a non-sense mutation was created that removes nine residues.

To verify this hypothesis, a homogenous mutation I12S serving as the control to the I12T mutation was created to examine the hydrogen bonding effect on enzymatic activity.

Utilizing a splice site targeting knock-in approach, a 4 nucleotide mutation was created to convert the 5′ splice site of Col2a1 exon 2 from a weak, non-consensus sequence to a strong, consensus splice site.

An animal model of the most common MYH9 mutation was created in my lab and demonstrated hematological abnormalities similar to those found in humans.

D474N mutation was created by PCR as described [25].

Depending on where the mutation is created, it may lead to cell death or transformation.

Therefore, primers for each mutation were created and used on IDH1 wt cDNA in pDONR221 (DKFZ clone repository).

Transposons are excellent mutagens, and when a mutation is created by a known transposon, it is possible to clone and sequence the causal gene (Walbot 1992).

30 A topological file containing hybrid amino acids for all point mutations was created with a VMD plugin called Mutator, based on standard Chemistry at HARvard Molecular Mechanics (CHARMM) topology.

A human HSF1 mutant containing both the S303A and LZ4m mutations was created and its ability to promote human HSF1-dependent yeast growth was compared to the individual HSF1 mutants as well as wild-type HSF1 in quantitative cell growth assays.