Sentence examples for mutation was expected from inspiring English sources

Thus, the DSE mutation was expected to reduce mRNA levels.

This mutation was expected to allow for spontaneous disulfide bonding and STAT1 homodimerization as described for STAT3 [25].

The Y417A mutation was expected to prevent the formation of the key hydrogen bond with the ligand.

The E1836K mutation was expected to perturb this interaction network, and it was therefore surprising that this variant does not dramatically reduce phosphopeptide binding.

As a homozygous mutation was expected, a primary filter for variants with a frequency of at least 50% reduced the list to 6721.

Based on the online TMD prediction algorithm (http://dgpred.cbr.su.se/ ), no mutation was expected to change the N-terminal or C-terminal boundaries of the TMD.

The H547P, H547A, H547D, and H547R single mutations were tested because proline and alanine mutations are expected to be the most significant change in backbone conformation, while aspartic acid or arginine mutation is expected to introduce significant side-chain conformational disturbances due to their non-neutral electrostatic potentials.

The Y470H mutation is expected to destabilize the YYY motif by impairing both the Y470-Y548 and Y470-Y551 interactions, whereas the Y548H and Y551H mutations are expected to partially reproduce the effect of Y470H, as they only impair one of the Y470-Y548 and Y470-Y551 interactions.

Where, the crossover and mutation rate are determined by the traditional selection method trial-and-error based on the principle of crossover is expected to be higher while mutation is expected to be lower [32], which respectively equal to 0.2 and 0.02.

Hence, the S259V mutation is expected to impair the receptor capability to effectively bind PTC and to be activated, in an indirect fashion.

The mutation is expected to affect cell-cycle progression [ 25].