Sentence examples for mutation was first from inspiring English sources

In 2008, the R132H IDH1 mutation was first found in human glioblastoma multiforme [55].

To test this, the pdc2Δ519 mutation was first integrated by transformation and homologous recombination into the genome of the commercial EC1118 and the native Mab2C wine yeasts.

This process of evolution of activity by selection and mutation was first utilised ex vivo in phage display technology [2] and later using yeast or bacteria as vectors.

This mutation was first identified in families with aminoglycoside-induced deafness, and the ototoxic susceptibility was attributed to enhanced binding affinity to aminoglycosides of 1555A>G rRNA (Qian and Guan, 2009).

This mutation was first reported by Benson et al. who found similar electrophysiological defects in tsA201 cells [16].

The mutation was first mapped on chromosome 3 by bulk segregation analysis (BSA).

Furthermore, the true prevalence of nondeletional mutations and Thailand type (− THAI) deletion mutation were first reported in this study.

An example of this may be an escape pattern where a primary mutation is first selected in context of a specific HLA allele, followed by a compensatory mutation at a secondary site [24], [35], [36].

In this assay, a mutant DNA with one base mismatch (C→G mutation) is first hybridised to a complementary DNA modified magnetic NP.

DNMT3A somatic mutations were first discovered by Yamashita and colleagues following sequencing of tissue from adult patients with de novo acute myeloid leukemia (AML) (Yamashita et al., 2010).

IDH mutations were first observed in human gliomas [ 102].