Sentence examples for mutation occurred first from inspiring English sources

However, it was impossible to determine from our data whether the mutation occurred first in the S form or in the M form.

For 4 of the 6 populations where sterile aggregates were observed, the aggregate mutation occurred first.

Models in which the recombination or mutation occurred first produce the same end product but proceed through different intermediates, corresponding to C26 or C22, respectively (Table S3).

These data suggest that the rs4917639 mutation occurred first, and that rs1799853 and rs1057910, which are diagnostic for *2 and *3, arose independently on the same parent allele.

Conversely, for population RMB1-G05, the presence of steriles and sterile aggregates (but not nonsterile aggregates) indicates that the sterile mutation occurred first and that the aggregate mutation occurred in the sterile background.

This might suggest that the 153C to T mutation occurred first, within the source gene, and was propagated before the 174G to A mutation took place within the same source gene.

Based on the previous finding that the major component of efficiency in mutator pathways is due to initial mutator mutations [15], we evaluate the mutator pathway assuming the mutator mutation occurs first.

The mutator pathway probability of carcinogenesis is evaluated assuming the mutator mutation occurs first.

This apparent problem can be explained by the fact that a third hormone, 11-deoxycorticosterone (DOC) can still bind; therefore, the receptor can still be functional (in a different manner) if the S106P mutation occurs first.

In the alternative model, a deleterious mutation occurs first, being subsequently compensated by a second-site substitution.

How would a random genetic mutation occurring first in an isolated single organism possibly become fixed in a population?