Ai Feedback
Exact(6)
Since 16S rRNA makes very specific contacts with many different ribosomal proteins and with other parts of itself, the pace at which spontaneous random mutation can change the sequence of the bases in the rRNA is slow.
It is worth mentioning that, in principle, one point mutation can change the oligomerization state of the coiled coil.
In some cases, the clinical penetrance of a particular mutation can change quite dramatically with age.
Importantly, a given mutation can change from a passenger to a driver aberration should the selective pressures change.
For instance, mononucleotide polymorphic mutation can change aa position 55 from Ala to Thr, which subsequently affects long-chain fatty acid hydrophobicity, fatty acid oxidation, and insulin resistance.
In one type of transition, alteration in the parameters that characterize the regulatory network interactions (e.g., by mutation) can change the landscape topography: flattening a hill here, deepening a valley there, etc., thereby influencing the course of the gravity-defined trajectories of the ball/cells.
Similar(54)
Mutations can change the amino acids that a gene codes for, and hence the nature of the coded protein, or they can change the way that transcription factors do (or don't) bind to a given regulatory region.
In addition to resistance issues, HA mutations can change the tropism of viral binding (upper vs. lower respiratory tract binding) and the antigenicity of the virus.
Point mutations can change gene length in a few ways.
Even a few mutations can change the input from AND to OR or single input switches, suggesting that regulation is quite plastic and evolvable.
Numerous studies have shown that fruitless loss-of-function mutations can change the morphology of both central and sensory neurons (Kimura et al., 2005; Mellert et al., 2010) and the survival of central neurons (Kimura et al., 2005).
Related(20)
flux can change
mutation can shift
move can change
variation can change
evolution can change
shift can change
transformation can change
mutation can inhibit
mutation can have
mutation can alter
mutation can modulate
mutation can induce
mutation can cause
mutation can suffer
mutation can be
mutation can prevent
mutation can provoke
mutation can inherit
mutation can give
mutation can associate
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com