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Mutation, as determined by testing a uniform random number against the mutation rate (1e−4 and 1e−6) for each chromosomal element, occurs after the new chromosome is created.
Mutation, as determined by testing a uniform random number against the mutation rate (1e−3 or 1e−5) for each chromosomal element, occurs after the new chromosome is created.
Mutation, as determined by testing a uniform random number against the mutation rate (1e−3, 1e−4, 1e−5) for each chromosomal element, occurs after the new chromosome is created.
CCF column indicates fraction of neoplastic cells that harbor the mutation as determined by ABSOLUTE.
Seven of the 15 samples investigated revealed at least one somatic heteroplasmic mutation as determined by denaturating HPLC analysis (DHPLC).
Eligible patients had unresectable stage III or stage IV melanoma harboring the BRAF-V600E mutation, as determined by the cobas 4800 BRAF V600 mutation test.
Similar(51)
Differences in proportions of breast cancer patients with a family history and other clinicopathological characteristics were tested for an association with the BRCA1 and BRCA2 mutation status, as determined in our research cohort, using the Pearson's χ-test.
Tumors from patients in this study harbored several EGFR mutations exon 19 deletion, exon 21 point mutation (L858R), or exon 18 point mutation (G719C, G719S, and G719A)—as determined by direct sequencing or the PNA-LNA PCR Clamp method.
Typically, 25 50% of cloned shRNA constructs contain significant mutations as determined by DNA sequencing.
Exposure of TM3 testicular Leydig cells to arsenic results in the changes in DNA methylation and mutations as determined by random amplified polymorphic DNA (RAPD) [ 4].
To evaluate the performance of MAC, 10 lung squamous cell carcinomas (LUSC) samples with the highest level of somatic mutations as determined by whole exome sequencing, were selected from 178 TCGA (The Cancer Genome Atlas LUSCC tumor samples (https://tcga-data.nci.nih.gov/tcga/dataAccessMatrix.htm).htm
Related(20)
shift as determined
flux as determined
transfer as determined
evolution as determined
assignment as determined
transition as determined
variation as determined
abnormality as determined
transformation as determined
mutant as determined
mutation as compared
mutation as opposed
mutation as illustrated
mutation as discussed
mutation as described
mutation as indicated
mutation as shown
mutation as tested
mutation as contrasted
mutation as predicted
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