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Exact(9)
The Km values of mutants were increased compared to native form, indicating lower affinity of mutants toward substrates.
The organic solvent tolerance levels of these mutants were increased in the following order: JA300 < JA300 acrR IS < JA300 marR < JA300 acrR IS marR.
It has been shown that DnaK mRNA and DnaK protein of Streptococcus mutants were increased in response to acid shock (Jayaraman et al. 1997), and the strain's capacity for growth in low-pH media becomes impaired, when DnaK levels of S. mutans are lowered via knockdown, strongly indicating the involvement of DnaK in acid tolerance (Lemos et al. 2007).
Notably, the A z values of both mutants were increased from 3.1 to 4.2 mT, larger than most of characterized native CuA sites.
Oocyte numbers in the Notch2 conditional mutants were increased not by excess or extended cellular proliferation, but as a result of decreased oocyte apoptosis.
Support for this comes from the observation that the activities of AQVQMM and the individual UbcM2 mutants were increased in assays containing K48R Ub.
Similar(51)
In these mutations, the Km values are decreased and the kcat values are decreased, meaning that the affinities of the mutants are increased but the rates of the catalysis are decreased.
The lifespan of tax-4 p678 tax-4 p6781426) rrf-3 pk1426ts rrf-3 pk1426double these animutantsre fed wash smg-1 RNAincreased1), suggesting that tax-4 and smg-1 act independently to regulate lifespan.
Although growth rate of the mutants was less affected than wild type, the peak luminescence for two of the mutants was increased in the presence of Vp cell-free culture fluids whereas wild type luminescence was not increased (Table 5; Figure 6B).
In our conditions, the period of defecation in both clk-1 and clk-3 mutants is increased by about 40%.
When compared with Pomc −/− mice, obesity in Pomc −/−Tg + mutants is increased and the rate of weight gain is more rapid.
Related(20)
mutants were enhanced
mutants were grown
clones were increased
mutants were gained
mutants were raised
genes were increased
ones were increased
changes were increased
mutants were gain
mutants were named
mutants had increased
mutants displayed increased
mutants were confirmed
mutants were recovered
mutants were obtained
mutants were discovered
mutants were set
mutants were generated
mutants showed increased
mutants were monitored
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