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Similarly, in maize, Mu-insertional lox3-4 mutants displayed increased attractiveness to RKNs, and an increased number of juveniles and eggs were accompanied by elevated levels of JA [ 53].
Consistent with previous reports, Prkci mutants displayed reduced, and Foxo1 mutants displayed increased venous vascular coverage (Fig. 1d; Supplementary Fig. 2a 8,17.
These mutants displayed increased cytopathology and virus shedding into the extracellular medium.
The S270T and K874Stop mutants displayed increased time to channel inactivation and thus led to a gain of function in the TRPC6 cation channel.
dmib1 mutants showed defects in wing margin specification, leg segmentation, and vein determination, while dneur mutants displayed increased numbers of neuroblasts and sensory organ precursors [9], [10].
At these temperatures, we observed that Df 2L dLRCH mutants displayed increased lethality (Figure 6B), indicating that dLRCH activity contributes to the robustness of the fly when placed in harsh environmental conditions.
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We expect that this assay will be useful for the engineering of additional mutants displaying increased activity toward non-native substrates.
Mutagenesis was followed by the screening of mutants based on cerulenin as an attempt to obtain mutants displaying increased lipid productivity.
Several novel genes in which mutants display increased spore wall permeability were identified.
All these mutants display increased sensitivity to the drug 5-Fluorouracil (5-FU) [12], which is imported by Fur4.
First, when assessed genetically, many of the mutants display increased non-disjunction of homologous chromosomes (reviewed in [17]).
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