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The fibrils formed by the mutants were different to the ones derived from the wild-type peptide.

Finally, we tested whether any of the mutants were different in response to aromatic compounds not known to activate wild-type HbpR.

In accordance with the severe vascular tissue defects observed in both hypocotyls (Figure 7A) and stems (Figure 8A), the infrared absorbance spectra from esk1 mutants were different from those of wild type.

At the same concentration of wild-type protein, we observed that mutants R18A, I141A, L143A, E153A, C376A/G377A, Y393A, I432A, V566A and V571A had an approximately 2 7 fold decrease in DNA binding affinity as compared with wild-type protein (P<0.05), and the band patterns of these mutants were different (Fig. 5 B).

It was found that the E255A, K271A, K272A, E273A, and E275A mutants were different from the E256A and R276A mutants because they yielded mature 170 kDa P-gp as their major product.

Also, markers of cell death pathways in these two groups of mutants were different; the results suggest that the caspase-dependent pathway was activated in mice with missense mutations and the caspase-independent pathway was activated in mice with PLP1 duplications (see the Introduction section).

Similar(54)

Their expression patterns of 16 OsOPT genes and phenotypes of five OsOPT mutants are different.

The test showed (Figure 1A) that the proportion of mutants was different between those two data sets (p<0.05).

As protein stability has been linked to protein subcellular localization we investigated whether the half-life of the NLS and NES mutants was different.

Our observation of reduced melanin in the serotype A and D pmt4 mutants is different from a prior report in which no melanin defect was observed in a serotype A pmt4 mutant [22].

Third, the effects of tumor-associated BRCA1 mutants are different between the EREL site of IGF-1 and consensus ERE.

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