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In the end, the doctor wouldn't see a remission of the patient's cancer if driver mutations were different across its metastases.
Yet even though the squamous cell cancers analyzed in the study often had mutations in genes for these enzymes, the genes and the mutations were different in different patients.
All mutations were different, indicating a lack of a founder effect in the form of jackpot mutations.
The complete list of 129 mutations (111 mutations were different) found in exons 1 and 2 of RASSF1A in all experiments is shown in Table S1A.
The type and frequency of TDR-associated mutations were different among different HIV-1 subtypes.
All mutations were different missense mutations, and were shown to occur de novo.
Similar(48)
The mean number of mutations was different between African-Americans (151.31) and European-Americans (277.63).
The development of genotypic mutations was different in CSF and plasma, suggesting discordant viral evolution.
In the two species, the mutations are different, and the molecular mechanism by which less melanin is produced is different, too.
Although the phenotypes arising from these mutations are different, suggesting different mechanisms of pathogenesis, we present evidence that apoptosis may be the final common pathway of the disease process linking genotype to phenotype.
And even in one embryo harboring mutations, the somatic mutations are different [ 5, 33].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com