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The mprF mutants have higher LPG/PG ratios in the membrane outer leaflet and bind less daptomycin than the wild-type strain.
Consistent with this possibility, we also observed that the cell bodies of uev-1 mutants have higher levels of GLR-1 GFP GLR-1 GFP observed in wild-than animals (Figure 5A, C, K).
Another reason could be that rpoB mutants have higher fitness under the clinical conditions encountered by these strains.
Interestingly, maize plants with white endosperm (yellow mutants) have higher moisture than those with yellow endosperm [ 16].
Seventh, PINK1 MUL1 and parkin MUL1 double null mutants have higher Mfn levels as compared to single null mutants of MUL1, PINK1, or parkin.
Moreover, there is initial evidence from a recent study that TRAIL death receptor-specific mutants have higher specific activity than the wild-type molecule.
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Despite extensive mutagenesis, Sso7d mutants have high thermal stability; five of six mutants analyzed have melting temperatures > 89 °C.
DIM mutants have high cell wall permeability and are severely attenuated in mouse models of TB [25], [26].
Both mutants have high levels of recombination, chromosome loss, as well as synthetic growth defects with rad52, mec1 [15], [15] and other genes that are involved in DNA metabolism.
Also, jetlag mutants have high CRY level, which can counteract PDFR signaling (preliminary behavior data).
Consistent with this biochemical mechanism, PGCs in blastoderm-stage pgc mutants have high levels of CTD-PSer2.
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