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Exact(5)
In contrast, the C-cut mutant was localized in the cytoplasm and lost ability to induce neurites and spines (Fig. 8A and B).
We observed that the YF mutant was localized to the nucleolus at a higher level compared with the wild type.
The results indicate that, 30 min following starvation, only the WT Beclin 1, but not the mutant, was localized to punctate spots with the cells.
Only a small fraction of the fs230 mutant was localized to the Golgi apparatus, whereas a large population of the mutant was retained within the endoplasmic reticulum.
The most noticeable change in the Ile mutant was localized around the site of mutation: the side chain of Glu322, adjacent to Ile319, is oriented perpendicular to its original conformation in the free and ubiquitin-bound forms of Sst2cat.
Similar(55)
It is known that the C181S mutant is localized mostly to the Golgi whereas the C184S mutant is localized mostly to the PM.
In summary, changes in histone modifications in the nst triple mutant are localized to the Tel VR-targeted hph allele, with the exception of a general effect of reduction of H3 trimethyl-K27.
A majority of the genes up-regulated in both hha/ydgT and hns/stpA mutants was localized in and around H-NS-binding regions classified as 'coding' (108 genes; 88%; Supplementary Fig. S3), including those covering multiple coding sequences.
Immunofluorescence microscopy and enzymatic digestions demonstrated that full-length peripherin/rds and the four C-terminal deletion mutants were localized to intracellular membranes and were all Endo-H sensitive.
Both mutants are localized in the nucleus as wild type EBV-Z (data not shown).
A majority of the wildtype and Salmonella T3SS mutants were localized intracellularly (>60% of total bacteria counted), and no significant difference in bacterial localization was observed between wildtype and T3SS mutants, further demonstrating that Salmonella can invade into 3-D HT-29 cells in the absence of SPI-1 and SPI-2 T3SSs.
Related(20)
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