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This contention is further supported by the finding that single S6K mutant mice fail to reveal a defect in T cell development [43], [44].
Offspring of these Clock mutant mice fail to thrive, suggesting that their milk production may not be adequate enough to nourish their young [100], [101].
Subsequently, mutant mice fail to thrive with the average weight of a mutant at P9 being 3.1 g compared to an average of 6.9 g for wild-type (n = 3).
Why do dbh mutant mice fail to exhibit the robust sleep phenotypes observed in NE deficient zebrafish?
Consistent with this model, agrin, MuSK and lrp4 mutant mice fail to form NMSs, lacking all features of pre- and postsynaptic specializations [22 24].
Indeed, Spnb4 mutant mice fail to initiate action potentials and show progressive behavioural deficits with altered network excitability (Uemoto et al., 2007; Yang et al., 2007; Winkels et al., 2009).
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In addition, we observed the majority of mutant mice failed to impregnate their mates, because vaginal plugs were not found after mating.
In contrast, mutant mice failed to exhibit any improvements over trials, suggesting that the striatal neurons are indispensable for motor learning.
In particular, axons in β1-Integrin mutant mice failed to respect muscle boundaries and grew onto the tendon organ.
Whereas TLR9 mutant mice failed to respond to exogenous histones, we observed increased damage in TLR4 KO, TLR2 KO, and TRIF KO mice (Supporting Fig. 2).
As the process continued, most COCs of mutant mice failed to ovulate and these follicles were left in the ovaries and turned into atretic follicles.
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mutant mice deficient
mutant mice failed
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mutant proteins fail
mutant worms fail
mutant embryos fail
mutant disks fail
mutant mice have
mutant alleles fail
mutant plants fail
mutant neuroblasts fail
mutant bacteria fail
mutant mice produce
mutant females fail
mutant larvae fail
mutant mice live
mutant males fail
mutant GMCs fail
mutant parasites fail
mutant forms fail
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