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Figures 1B D explore the stage at which the mutant males fail.
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If males fail to achieve orgasm then no reproduction occurs.
Sumatran males fail to meet two requirements and Bornean males fail to meet all three.
These considerations notwithstanding, the transgenes expressing mutant MLE proteins clearly failed to rescue mle1 mutant males.
However, the progeny of homozygous mutant females fail to develop beyond 9.5 days p.c., and homozygous mutant males are sterile (Bourc'his et al. 2001; Hata et al. 2002; Bourc'his and Bestor 2004).
The mutant males are released into the wild, where they mate with females, fertilizing their eggs; after the eggs hatch into larvae, they die.
Hemizygous mutant males were generated by crossing heterozygous knockout females to C57BL/6 males.
fruA mutants males were the least affected, and fruC mutant males the most affected.
miR-124 mutant males exhibited increased male male courtship and reduced reproductive success with females.
miR-124 mutant males were rarely selected in the presence of a wild-type male, but females did not distinguish between CS males and rescued mutant males.
We observed chaining among groups of miR-124 mutant males.
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