Sentence examples for mutant is sufficient from inspiring English sources

The RB-K530A (K) mutant is sufficient to inactivate the E2F-binding pocket, whereas the RB-N757F (N) mutant is sufficient to inactivate the LxCxE-binding pocket.

These results confirmed that cleavage of the inhibin α-subunit occurs at the consensus cleavage motif and that mutagenesis of only the last arginine (the RARA mutant) is sufficient to abolish C-terminal proteolytic processing.

Wild-type MYO2 expressed in myo2Δ cells, or in the myo2Δ vps45Δ mutant, is sufficient for cell viability.

Taken together, these data suggest that the residual SUMOylation of Ago2 observed for the K402R mutant is sufficient to maintain RNAi activity of Ago2.

However, neither any difference during the onset of growth nor in the long term viability (K. Athenstaedt, unpublished result) between lro1Δdga1Δ and wild-type has been observed, indicating that even the reduced amount of TAG in the double deletion mutant is sufficient for balanced growth.

In regards to mutations themselves, the R882H DNmutantutant was sufficient to promote tumorigenesis in an IL-3 dependent transformation assay in leukemic 32D cells (Yan et al., 2011).

Neither the C79A nor the C308A single mutant was sufficient to prevent the dimer formation.

Addition of the CCISL motif to the C-terminal truncation mutant was sufficient to restore normal Rab25 localization.

Overexpression of wild-type Sirt1, but not the deacetylase-dead mutant, was sufficient to induce autophagy in ECs.

Strikingly, restoration of mannan core branching in the mptC mutant was sufficient to fully complement the in vivo phenotype in embryos.

Accordingly, we show that tethered NOT1 and a catalytically inactive POP2 mutant are sufficient to cause PABP dissociation from bound mRNAs in the absence of deadenylation.