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Exact(22)
In Arabidopsis, the rad51−/− mutant is viable, but sterile [24].
In support of this, although a TORC null mutant is viable and fertile [4], CREB mutants are lethal [23].
The dutΔ (deletion) mutant is lethal in E. coli, but the dut-1 partial inactivation (point mutation) mutant is viable and sensitive to the presence of uracil (10 mM) or an analog of uracil, 5FU (50 µM) [11], [17].
We observe that a degP mxiJ mutant is viable at 30° and 37°.
Interestingly, this quadruple mutant is viable when coutilizing glucose and acetate.
On the other hand, the Dvps35 mutant is lethal, but the Dsnx3 mutant is viable.
Similar(38)
The TbPLA1 null mutant was viable, and procyclic and bloodstream forms of the parasite were deficient in lysoPC synthesis.
The mutant was viable with a large reduction in enzymatic activity as CTP phosphocholine cytidylyltransferase detected in vitro using a firefly luciferase assay.
Strikingly, cells in which endogenous Mps1 was replaced with this mutant are viable but missegregate chromosomes frequently.
The double mutant was viable and displayed changes in gene expression similar to those of the single mutants (Additional file 1: Table S2).
Recent experiments have shown that ES cells expressing a ubiquitin ligase-deficient BRCA1-I26A mutare are viable and do not undergo spontaneous chromosomal rearrangements (Reid et al, 2008).
More suggestions(15)
mutant is thrombin-specific
mutant is unable
mutant is highlighted
mutant is hypersensitive
mutant is deficient
mutant is sufficient
mutant is resistant
mutant is selective
mutant is insensitive
mutant is immune
mutant is similar
mutant is functional
mutant is indistinguishable
mutant is consistent
mutant is incapable
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