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A tps1Δ mutant is deficient in trehalose accumulation.
This mutant is deficient in a peptide transporter expressed in the intestine [30].
For example, the BCR-ABL Y177F mutant is deficient in GRB2 binding, but still activates RAS in 32D and BaF3 cells, likely via SH2 domain dependent interaction with GRB2 and SHC [15].
The ethylene insensitive 2 (ein2) mutant is deficient in ET signalling, and the fatty acid desaturase 3/7/8 (fad3/7/8) mutant is deficient in JA biosynthesis.
Firstly, the pfk2 but not pfk1 deletion mutant is deficient in NADH-mediated glycolytic oscillations.
The vte1 npq1 double mutant is deficient in two major O2 quenchers, vitamin E (tocopherols) and the carotenoid zeaxanthin [ 47].
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Figure 8A shows that the hfq deletion mutant was deficient in both swimming and swarming motility.
The double dcl2 dcl3 mutant was deficient in a stress-induced increase in HRF in response to UVC; whereas, the triple dcl2 dcl3 dcl4 mutant was deficient in response to UVC and cold.
An isogenic ΔSP1732 mutant ST1601 was used as positive control for nasal colonization since our preliminary study showed that this mutant was deficient in nasal colonization (data not shown).
For example, TDM extracted from the cell envelope of a pcaA knock-out mutant, was deficient in cis-cyclopropanated α-mycolic acids and was shown to be hypoinflammatory [12].
One Arabidopsis mutant was deficient in HMGR, known to coarse-regulate sterol biosynthesis.
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