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Supporting this concern, the AQP1 N76S mutant developed a proton conductance, but mediated a WT water-flux (39).

We showed that organotypic cultures expressing the fs260 mutant developed a thinner stratum corneum thickness and exhibited parakeratosis.

The Congo red assay on M9-CR agar plates showed that the WT and complement strains developed a bdar morphotype and the ΔtolC mutant developed a pdar morphotype, suggesting that the ΔtolC mutation reduced curli production.

In particular, organotypic cultures grown from cells expressing the fs260 mutant developed a thinner stratum corneum with nuclei often present and an enlarged vital layer when exposed to acetone.

Upon reconstitution with Fe(II), but in the absence of 2OG, both ALKBH4 and the C15A/C17A mutant developed a broad and composite absorption band, extending from 400 nm (λ=404 nm, ϵ≈570 M−1·cm−1) to 600 nm (λ=490 nm, ϵ≈260 M−1·cm−1).

Similar(55)

Similarly, mice that express a cytoplasmically truncated type II receptor, which acts as a dominant-negative mutant, develop a degenerative joint disease resembling human OA [ 8].

Instead, the gi mutant develops a large rosette of leaves and thus is "gigantic" in size compared to wild type plants before finally flowering.

For example, the glp-1 (e2141ts ) mutant develops a gonad with no germ cells at the restrictive temperature of 25° and lives longer than the wild type (WT) (Arantes-Oliveira et al. 2002).

Transgenic mice expressing CMT type 1C-linked human SIMPLE mutant develop a late-onset motor and sensory neuropathy associated with abnormal myelin infolding, paranodal defects, and altered nodal organization (Lee et al., 2013).

The resulting mutants developed a severe aneurysmal arterial trunk that resulted in embryonic lethality during late gestation.

The resulting Ilk mutants developed a severe aneurysmal arterial trunk that resulted in embryonic lethality during late gestation.

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