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Exact(5)
All other comparisons were made at the 0.025 level to compensate for the multiple secondary endpoints.
A hierarchical procedure will be used to control type I error and handle multiple secondary endpoints analyses.
There were multiple secondary endpoints including ACR20/50/70 response, DAS28 less than 3.2, DAS28 less than 2.6, simplified disease activity index (SDAI) of 11 or less, SDAI of 3.3 or less, which were also planned for week 78.
Overall, the results from multiple secondary endpoints assessing lung function, asthma symptoms, and rescue medication use supported the superior efficacy of the combination product compared with fluticasone, formoterol, and placebo.
There are multiple secondary endpoints including systolic and diastolic blood pressure, random cholesterol, HDL cholesterol, ApoA1 and ApoB apolipoproteins, CVD risk score as assessed by the UKPDS risk engine (version 2) [ 42] and additionally in London only, a measurement of arterial stiffness assessed by pulse wave velocity.
Similar(55)
Even though the primary endpoint is to investigate comparative effectiveness among patients who have been exposed to at least one TNF-α inhibitor, CERTAIN will also enroll naïve to biologic agents patients in order to address multiple additional secondary endpoints and inform comparative safety research.
Multiple secondary effectiveness and safety endpoints will be addressed by investigating the entire population enrolled (naïve and biologic experienced).
The Bonferroni-Holm method was used for corrections for multiple measures of the secondary endpoints (Table 2) (Holm 1979).
The Bonferroni-Holm method was used to correct for multiple testing of the secondary endpoints presented in Table 3.
P values (not adjusted for multiple comparisons) are reported for secondary endpoints.
Estimating mortality due to the etiologies of pneumonia and diarrhea relies on secondary endpoints and multiple assumptions about those endpoints.
Related(20)
various secondary endpoints
numerous secondary endpoints
several secondary endpoints
many secondary endpoints
multiple secondary positions
multiple correlated endpoints
multiple secondary structures
multiple collaborative endpoints
multiple secondary transmitters
multiple secondary oscillators
multiple primary endpoints
multiple noncanonical endpoints
multiple secondary complications
multiple secondary data
multiple secondary metabolites
multiple secondary paths
multiple secondary users
multiple secondary antibodies
multiple unpredictable endpoints
multiple functional endpoints
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