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These data identify multiple noncanonical endpoints that are pivotal for rational design of hedgehog modulators and provide a new therapeutic avenue for obesity and diabetes.
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The interface allows one to upload a PDB structure to be modified by single or multiple noncanonical amino acids and/or simultaneously mutated.
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is another key glycolytic enzyme which may play multiple noncanonical functions implicated in cell growth and survival by hypoxic-independence pathway.
The closed testing procedure was applied for multiplicity considerations of multiple primary endpoints.
James is the vice president and general manager EMEA of Blue Jeans Network, a cloud-based video conferencing service that enables interoperability between multiple video endpoints.
To explore the value of multiple clinical endpoints in the unique setting of ovarian cancer.
Multiple secondary endpoints will include each of the components of the primary endpoint, the need for additional procedures, angiographic status at 1 and 3 years measured by an independent quantitative coronary arteriography laboratory, and measures of quality of life.
The combined use of the multiple novel endpoints shows a huge potential for use in toxicology.
Multiple efficacy endpoints were evaluated in this study.
Several studies have evaluated multiple clinical endpoints, but the approach taken in integrating results across these multiple endpoints has varied.
Further, it incorporates both a relatively large number of KRAS wt patients and multiple clinical endpoints.
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CEO of Professional Science Editing for Scientists @ prosciediting.com