Sentence examples for multiple primary breast from inspiring English sources

Multiple primary breast and ovarian cancer patients diagnosed with an initial breast cancer at or prior to age 50 may represent a distinct subgroup of women with a germline mutation that confers susceptibility to both breast and ovarian cancers.

Multiple primary breast and ovarian cancer cases whose initial breast or ovarian diagnosis occurred in 1970-1989 and a random sample of single primary breast or ovarian cancer controls diagnosed in the same years were identified through tumor registries at Duke University Medical Center and the University of North Carolina.

Multiple primary breast cancers were also considered (Table 4).

In cases with recurrent disease or second or multiple primary breast cancer, only the first primary tumour was included.

To the best of our knowledge this study is the first to demonstrate an association between a POLQ SNP and increased risk for multiple primary breast tumors.

An increased risk of multiple primary breast cancers (OR 5.7 6.5) has been reported in individuals carrying this CHEK2 1100delC allele [ 11, 21, 22].

Among the unselected breast cancer patients, the ivs38-8T>C polymorphism tended to be associated with an increased risk of multiple primary cancers (breast cancer and at least one other non-breast cancer) (OR 2.56, 95% CI 1.23 5.35, p = 0.02, Fisher's exact test, Table 2)., but the result did not reach statistical significance and was not seen among the familial cases.

The most common initial primary neoplasms in cancer survivors with multiple primaries were breast (29%), prostate (14.9%), and colorectal (9.0%) sites.

The questions regarding FH in the cross-sectional study focused on features that have been associated with an increased likelihood of clinically significant BRCA mutations, such as early-onset, bilateral or male breast cancer, multiple primary cancers of the breast and ovary, first-degree or multiple-case family history of breast or ovarian cancer.

A 52-year-old female developed multiple primary malignancies (liposarcoma, breast cancer, malignant histiocytoma, occult adenocarcinoma).

BRCA2 is associated with multiple primary tumours including breast, colorectal, ovarian and other cancers.