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The two p-GGNs were considered to be multiple primary lung cancers.
The feasibility of analyzing genomic instability expression profiles to distinguish multiple primary lung cancers from metastatic tumors was evaluated.
Distinguishing between multiple primary lung cancers and metastatic tumors is often difficult when the tumor histology is same.
Thus, in each patient these neoplasms could represent (i) multiple primary lung cancers, or (ii) primary lung cancer and derived metastatic lesions.
Therefore, one way to tackle this predicament is to explore new practical techniques and markers to diagnose and prognosis for multiple primary lung cancers.
The 5-year survival of patients with synchronous multiple primary lung cancers has been reported to range from 0%to44%4% despite an early diagnosis [ 11- 14].
Similar(42)
For patients with multiple, apparently separate, primary lung adenocarcinomas, each tumour should be evaluated.
We report a case of simultaneous acute bilateral lower limb ischemia, bilateral renal infarction, splenic infarction and cerebral infarction as a result of multiple emboli originating from primary lung malignancy invasion of the left atrium.
When additional tumour nodules are found synchronously with a known lung cancer, the distinction between lung metastases and multiple primary tumours has relied on clinical and morphological criteria [24].
Ten of the 67 patients with AAH and primary lung carcinoma (15%) had multiple primary cancers (range 2 6), all of which were adenocarcinoma.
Although frequently multiple, bilateral nodules are seen (Fig. 6A); a solitary nodule mimicking primary lung cancer may also be seen (Fig. 5A).
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