Sentence examples for multiple phenotypes with from inspiring English sources

The association between epilepsy and headache (especially migraine) is particularly interesting, as there are all common medical disorder that has multiple phenotypes with complex and poorly understood underlying mechanisms.

If the potential for an AKT1x COMT gene-gene interaction is taken into consideration in future association studies, we would predict that the minor A allele of AKT1 rs1130233 might strengthen associations between COMT Val/Met and the multiple phenotypes with which it has been associated, including cognitive function, schizophrenia and cancer.

Thus, genetic interactions affect multiple phenotypes, with each phenotype contributing independent information.

When treated with 17β-estradiol, female ACI rats (Rattus norvegicus) rapidly develop mammary cancers that share multiple phenotypes with luminal breast cancers.

Asthma is a heterogeneous disease and includes multiple phenotypes, with differing underlying disease pathogeneses, commonly recognised phenotypes include allergic asthma, non-allergic asthma, late-onset asthma, and asthma with obesity [ 26].

From the point of view of the survival of the flattest and natural selection, the appearance of multiple error thresholds is just a consequence of the existence of multiple phenotypes with different trade-offs between replicative ability and mutational robustness [ 18].

Further analysis of the hsf1-R206S, F256S allele revealed that these cells also displayed multiple phenotypes consistent with reduced TOR signaling.

We presume that the multiple phenotypes associated with corazonin neurons reflect multiple primary effects of altered corazonin neuropeptide secretion as well as secondary indirect actions.

Unlike other transcription factors tested, Hsf1 is unique since cells constitutively activated for Hsf1 hsf1-R206SS, F256S cells) specifically display multiple phenotypes consistent with reduced TOR function.

Multiple phenotypes associated with the mutation amyc are small colony size including, increased cell wall thickness, and non-hyphal, multipolar budding growth under restrictive conditions.

Genetic studies in Drosophila have shown that downregulation of mfn or overexpression of drp1 suppresses multiple phenotypes associated with lack of PINK1 or parkin, including defects in mitochondrial integrity, cell death, tissue health, and flight ability (Deng et al., 2008; Poole et al., 2008; Yang et al., 2008).