Sentence examples for many phenotypes with from inspiring English sources

This suggests that although tgr2 shares many phenotypes with previously characterized mutations in these genes, it is unlikely to represent an allele of one of these genes.

clu mutants share many phenotypes with park and PINK1 mutant flies, including flight muscle defects and sterility (Clark et al., 2006; Cox and Spradling, 2009; Greene et al., 2003; Park et al., 2006; Sen et al., 2013).

In contrast to a GWAS, which tests many SNPS for association with 1 phenotype or a few phenotypes, a phenome-wide association study explores the relations of many phenotypes with 1 SNP or a few SNPs (16).

Some species are strict diet specialists with extreme morphologies, but a considerable number present intermediate diets and phenotypes, possibly as a result of adaptive ridges or multiple local optima (many phenotypes with equivalent or similar fitness) and geographical/temporal variation in resource availability.

Direct expression of Aβ1 42 in Drosophila neurons is a well-studied model exhibiting many phenotypes with potential relevance to AD (reviewed in Iijima-Ando and Iijima, 2010; Moloney et al., 2009) including decreased lifespan, neurological deficits, amyloid-like deposition in brain, compromise of memory processes and age-dependent neurodegeneration (Iijima et al., 2004; Ling et al., 2009).

Many phenotypes associated with clu mutants are shared with those of park and PINK1 mutant flies, both of which are essential for mitochondrial function, although clu mutants are in general much sicker (Clark et al., 2006; Cox and Spradling, 2009; Greene et al., 2003; Park et al., 2006; Yang et al., 2006).

Results The authors previously developed a zebrafish model for ML-II and showed that the embryos exhibited many phenotypes consistent with the human disease, including craniofacial defects.

This is due to the fact that many phenotypes correlate with the phylogeny of HMDP strains (i.e., genetically similar strains have similar phenotypes), and any SNP that correlates with these strain relationships will be falsely associated with the phenotype.

Herein we show that activation of FUS3 after germination dampens the expression of genes involved in the biosynthesis and response to the plant hormone ethylene, whereas a loss-of-function fus3 mutant shows many phenotypes consistent with increased ethylene signaling.

The recruitment of SIRT6 by specific transcription factors to help suppress gene transcription via H3 deacetylation have been used to explain many phenotypes associated with SIRT6 deficiency, including tumor development, cardiac hypertrophy, growth retardation, and lipid metabolism/liver inflammation.

The FOXO3A gene in particular has been strongly associated with human longevity and with many phenotypes linked to healthy aging, among which is the preservation of insulin sensitivity (Franceschi et al., 2005; Bonafè & Olivieri, 2009).