Previously we have demonstrated that the deficiency of BMAL1 is associated with an early onset of several phenotypes associated with normal aging [7].
Pain perception is one of the most complicated measurable traits because it is an aggregate of several phenotypes associated with peripheral and central nervous system dynamics, stress responsiveness and inflammatory state.
Also, previous studies demonstrated no differences in several phenotypes associated with cryptococcal pathogenesis in C. neoformans strain H99γ compared to wild-type C. neoformans [40] further suggesting that clearance of the acute infection with the transgenic strain was not due to attenuation.
Indeed, non-cell-autonomous behavior explains several phenotypes associated with neurological diseases.
Several phenotypes associated with these mutants suggested a defect in SPB duplication.
Increased protein degradation mediated by the loss of function of UBP6 suppresses several phenotypes associated with aneuploidy.
The tra1- L3733A allele resulted in several phenotypes shared with strains having mutations in the ada genes (Fig. 1c; Table 3).
There is no known human deficiency for CRP, but there are several phenotypes associated with lack of acute phase response (reviewed in Pepys and Hirschfield 2003).
Excessive glucocorticoid action has been implicated in the development of several phenotypes associated with metabolic syndrome, such as obesity and type 2 diabetes.
