Sentence examples for multiple mutational events from inspiring English sources

To further analyze combinational rare mutation genes in the pathway level mRNA expression, we iteratively combine mutated genes belonging to the pathway so that multiple mutational events on multiple genes can be considered into one mutational event.

In some passerine bird species, differing mutations that are not clearly related suggest the likelihood of multiple mutational events.

We observed more than two mutations in the A-1 F1 and D-1 F1 worms, suggesting multiple mutational events in these animals, most likely in both the germ cells and somatic cells.

The failure of experimental transplacental carcinogenesis to mirror human pediatric experience more closely may reflect the need for multiple mutational events in target cells, and for experimental carcinogens that are capable of causing the full spectrum of mutations that occur in cancer-related genes in pediatric neurogenic tumors.

Alternatively, multiple mutational events could have taken place independently in different strains in the province, resulting in a pool of pre-existing mutants that are selected through chemotherapy [10].

Oxyradicals are involved in multiple mutational events and can contribute to the conversion of healthy cells to cancer cells.

Microsatellite and genealogical analyses of eight separate European kindreds support multiple distinct mutational events at a cytosine-phosphate diester-guanidine dinucleotide mutation hot spot.

This study [ 20] was only a very preliminary attempt to confirm the same group's past speculation that the genetic basis for schizophrenia is multiple rare mutational events, perhaps in genes of relevant neuronal pathways [ 19].

Studies on these alleles led to the conclusion that early flowering types evolved by multiple independent mutational events from winter-annuals containing an ancestral functional FRI allele (FRI-wt) [ 25].

An alternative possibility to multiple separate mutational events being responsible for these apparently unconnected P102L IPD kindreds is that these small pedigrees do share a common ancestor with the large pedigree but that this was long enough in the past for linkage to the disease haplotype to have broken down.

Sequential SNPs can arise from single mutational events involving multiple base pairs or as a consequence of individual events at adjacent positions.