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Myosin binding subunit (Mbs) in D. melanogaster is involved in multiple developmental events including regulation of photoreceptor development in the compound eye [33].
This supports our original hypothesis that prenatal effects of cocaine and their inter-individual variability may involve the integrating circadian system, potentially causing desynchronization of multiple developmental events.
Throughout the insect life cycle, the steroid hormone 20-hydroxyecdysone (20E) coordinates multiple developmental events by eliciting a complex genetic program via a heterodimeric nuclear receptor composed of the ecdysone receptor (EcR) and ultraspiracle proteins (USP).
Arabidopsis miRNAs [ 27] regulate multiple developmental events.
miRNAs regulate multiple developmental events in plants.
The Wnt pathway participates in multiple developmental events during embryogenesis and has also been implicated in adult tissue homeostasis.
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The eggshell is required for multiple early developmental events, including meiosis, polar-body extrusion, osmotic barrier function and polarization.
Via promotion of the active GTP bound conformation of target GTPases, C3G has been implicated in the regulation of multiple cellular and developmental events including proliferation, differentiation and apoptosis.
While it is clear that LIS1 is essential for multiple cellular and developmental events, the cerebral cortical-specific mechanism that is distinctive from the housekeeping functions of LIS1 is yet to be defined.
Notch is a transmembrane receptor that mediates cell-cell communication events in multiple developmental contexts [65], [66].
This might be particularly important for functional dissection of BMP signaling in complex biological settings like in vitro ES cell differentiation, where BMP signals are required at multiple time points to regulate a number of diverse developmental events [10], [12], [14] [16].
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multiple developmental stages
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multiple developmental defects
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