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In this study, fault tolerance is set to three in e-PCR pipeline Step 2 to remove multiple loci as much as possible and increase the probability of the unique primers being aligned to reads from samples, while fault tolerance is set to one in e-PCR pipeline Step 3, given the tradeoff between InDel accuracy and SNP tolerance.

To reiterate, mutation combines information from multiple loci as it changes a certain locus.

The G. bethesdensis isolate from patient 5 was distinct from that of his brother (patient 2) at multiple loci, as determined by using the Granulibacter microarray chip.

I argued that the writing of mutations combines multiple pieces of information from alleles at multiple loci as it puts them into one mutation into one locus.

The other process is to pool all of the PCR products and prepare a single NGS library for each of the tagged multiple loci as a multiplex NGS library (singleplex PCR/multiplex NGS library model: Figure  1B (2)).

This implements a coalescent-based method that uses the concordance of gene trees across multiple loci as evidence for a particular species delimitation model, but does not rely on reciprocal monophyly for each individual locus.

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Similar(48)

Hypertension is considered a multifactorial disease – it is influenced by multiple genetic loci as well as environmental and lifestyle factors including diet, smoking habits and physical exercise.

MHC genotyping in species particularly suited for rigorous evaluation of such hypotheses, i.e. showing multiple MHC loci as well as among-haplotype variation in the number of loci, has been notoriously difficult since appropriate methods have not been available.

IBD is a complex disease, proposed to be an autoimmune disorder with the involvement of multiple genetic loci as well as a contribution of the gut microbiota in the development of the disease.

In a biological system, this corresponds to the situation of multiple contributing genetic loci, where the expression of the gene is affected by multiple trans-acting loci as well as a possible cis-acting locus through either an additive or an epistatic effect.

A blast search done with APH_1133 shows, for example, that Anaplasma marginale, as well as Ehrlichia and Wolbachia species, also have multiple loci annotated as TrbC/VirB2 family members (see additional file 8: Examples of other Anaplasmataceae bacteria with multiple virB2 loci).

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