Sentence examples for multiple kinase activities from inspiring English sources

Kinase substrate arrays can be used for parallel analysis of multiple kinase activities, which is called kinome profiling.

These arrays have now been used in mammalian and plant systems to analyze multiple kinase activities in parallel [29] [32].

Finally, the method developed here enables simultaneous measurement of multiple kinase activities within single cells.

Here we report that this platform can be applied to simultaneously measure multiple kinase activities from single adherent cells.

In myeloma, multiple kinase activities (FDR < 0.0014) were hypermethylated, and muscle/fiber related concepts (FDR < 9×10-5 for contractile fiber part) were hypo-methylated.

As such, for a given duration of IKK2 or IKK1 (a+b), there are multiple kinase activities within the library those differ with respect to peak amplitude (h) and peak onset time (a) (see Figure 1 figure supplement 2A).

Multiple kinase activity profiling from single cell lysate could potentially allow us to study heterogeneous activation of signaling pathways that can lead to multiple cell fates.

After receptor dimeri-zation, an activation cascade of multiple protein kinase activity and tyrosine autophosphorylation occurs, phos-phorylating several intracellular substrates including Ras-Raf-mitogen-activated protein kinase, phosphatidylinositol-3-kinase (PI3K -Akt, and other imPI3K -Aktignandng that regulates apotherimportantllular proliferation pathwaysignaling0].

Finally, we compare the binding affinities of multiple kinase inhibitors with the phosphorylation activity of their targets in our study.

Collectively our results suggest that CPT affects multiple pathways leading to diminution of kinase activities.

The recent study by Lemeer et al. suggests that a large number of protein kinase activities in developing embryos can be profiled using arrays of multiple standard peptide substances, suggesting a wide conservation of kinases between human and zebrafish[50].