Sentence examples for multiple kinase pathways from inspiring English sources
This effect was associated with the inhibition of multiple kinase pathways including MAPK, PI3K/AKT, and NF-κB signaling pathways.
On the other hand, the role of SHP-2 in multiple kinase pathways – including MAPK, JAK/STAT, and IGF – is well established.
Protandim (LifeVantage) is a dietary supplement that consists of five low-dose natural Nrf2 activators that activate Nrf2 through multiple kinase pathways [ 80].
Furthermore, SMAD4 loss causes alterations to multiple kinase pathways (particularly the phosphorylated ERK/p38/Akt pathways), and increases chemoresistance in vitro.
If it does, the data would reveal that bZIP63 is regulated by multiple kinase pathways to carry out its function in the energy transition response.
Moreover, EPEC prevents the phosphorylation-associated activation of multiple kinase pathways regulating IL-8 gene transcription by a mechanism apparently independent of LEE-encoded effectors and four non-LEE-encoded effectors.
Rather, it seems to be related primarily to an enhancement of phosphorylation at the downstream serine 305 residue via multiple kinase signaling pathways [ 10- 12].
The activation of multiple kinase signalling pathways leads to transcriptional effects independent of nucleolar RARs via transcription factors that lie at the end of these signalling cascades (Al Tanoury et al, 2013; see Figure 2).
In addition to the above, both superoxide and hydrogen peroxide contribute to endothelium-independent constriction through activation of multiple protein kinase pathways.
These findings point out that a splicing factor such as SPF45 may be regulated by multiple MAP kinase pathways which can result in alterations in splicing programs relevant to cancer cells.
Regulation of TP signaling itself is similarly complex, with multiple kinase-mediated pathways implicated in receptor desensitization, while oligomerization of the distinct TP splice variant products has also been implicated in modulating function [8], [9].
