Sentence examples for multiple kinase inputs from inspiring English sources

The major negative upstream regulator of mTOR is the TSC2 complex, which integrates multiple kinase inputs, including Akt and GSK3.

This effect was associated with the inhibition of multiple kinase pathways including MAPK, PI3K/AKT, and NF-κB signaling pathways.

Kinase substrate arrays can be used for parallel analysis of multiple kinase activities, which is called kinome profiling.

Upon extracellular stimuli multiple kinases, such as protein kinase A, protein kinase C and casein kinase II, phosphorylate CREB at serine 133 (P-CREB) leading to activation of immediate early gene c-fos [3, 4].

For instance, phosphatase sharing between multiple kinases is ubiquitous within the MAPK pathway.

The NSKI RV1088 targets multiple kinases.

In most cases, inhibitor knockdowns redundantly enhanced multiple kinases.

Multiple kinases, including PKA, cyclic GMP-dependent protein kinase (PKG), and protein kinase C (PKC), can regulate BK channel currents.

Most kinase inhibitors target the ATP-binding site common to all kinases, and can bind multiple kinases [ 17].

As kinases are far more numerous than phosphatases, one phosphatase must target multiple kinases.

Underwood et al.[ 15] demonstrated that the histidine kinase CD2492 can potentially serve as a phosphorylation donor for C. difficile Spo0A and proposed that other histidine kinases (i.e. CD1492 and CD1579) may also interact with Spo0A suggesting multiple environmental inputs.