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Moreover, HMGB1 can produce multiple inflammatory mediators through ER stress, which, in turn, promote liver fibrosis.
This enzyme is potentiated by its formation of multiple inflammatory mediators.
Diverse injuries are a consequence of multiple inflammatory mediators (complement, kinins, kallikrein, cytokines).
The wide suppression of multiple inflammatory mediators through single molecule could be highly advantageous in IBD management.
This shock could result from the interplay of the initial hypovolemia and the release of multiple inflammatory mediators.
Inflammation in cardiac surgical patients is produced by complex humoral and cellular interactions with numerous pathways including activation, generation, or expression of thrombin, complement, cytokines, neutrophils, adhesion molecules, mast cells, and multiple inflammatory mediators.
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Type 2 diabetes is characterized by activation of multiple inflammatory processes, mediators and pathways [ 40, 41]; vascular damage leading to atherosclerosis is a typical pathological consequence [ 42] partly mediated in fact by specific RAGE (receptor of AG E which initiate further cascades of inflammation [ 43].
Activation by C5a induces the release of multiple additional inflammatory mediators [ 106].
Ultraviolet radiation (UV) induces an increase in multiple cutaneous inflammatory mediators.
LPS acts directly at the brain endothelium but also activates multiple systemic inflammatory mediators and alarmins, which propagate the inflammatory signal throughout the body.
This assay allows measuring the concentration of multiple inflammatory-associated mediators in a single sample.
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