Sentence examples for multiple inflammatory conditions from inspiring English sources

Besides its function as a growth factor and neurotropic factor, PGRN was reported to have anti-inflammatory activities in multiple inflammatory conditions (Jian et al., 2013a).

This review analyzes the known implications of leptin in multiple inflammatory conditions, including autoimmune diseases, and how this knowledge could be instrumental in the design of leptin-based manipulation strategies to help restoration of abnormal immune responses.

CXCR4 also regulates the recruitment and invasion of immune cells like T-cells, macrophages, and neutrophils in multiple inflammatory conditions such as inflammatory bowel disease and lung inflammation.

Finally, citrullination occurs in multiple inflammatory conditions [ 8, 9], in the lungs of smokers [ 36], and in different cancers [ 37], and there may be a common role for citrullination in all of these processes that is important to understand.

The reported presence of extracellular HMGB1 in multiple inflammatory conditions and the beneficial effects of HMGB1 blockade in preclinical models of inflammatory diseases have thus led to the acknowledgement of HMGB1 as an inflammatory mediator with pathogenic functions in several inflammatory diseases (reviewed in [ 12]).

This is supported by elevation of catK levels after IL-1β stimulation in our in vitro studies and by reports by others in multiple chronic inflammatory conditions in vivo [ 7, 10, 39].

Continuous improvements in biopharmaceutical properties of diclofenac have led to the creation of a broad array of drug products designed to treat multiple inflammatory and painful conditions.

Although this response is helpful at initially protecting from invading pathogens, prolonged neutrophil responses mediate tissue damage in multiple organs under inflammatory conditions (Fukushima et al. 1995; Partrick et al. 2000).

Detailed studies of the biological roles of IL-22 have suggested that IL-22 is likely to exert multiple functions under inflammatory conditions because its signalling modulates the expression of many genes involved in chemotaxis, proliferation, innate immunity and inflammation (Zenewicz and Flavell, 2011; Rutz et al, 2013).

But given that this population of children carries an elevated risk for additional autoimmune (autoimmune thyroiditis, celiac disease, multiple sclerosis) and inflammatory conditions (atherosclerosis, depression, sleep disorders) (Dietert and Zelikoff 2009), insulin and glucose management alone is unlikely to correct underlying immune dysfunction.

Anakinra was the first IL-1 blocker to have shown efficacy in multiple autoimmune disorders and inflammatory conditions linked to NLRP3 mutations (MWS and NOMID).