Sentence examples for multiple endogenous genes from inspiring English sources

Coupling of dCas9 to a transcriptional repressor domain can robustly silence expression of multiple endogenous genes.

The CRISPR ChaCha is dose-dependent, reversible, and can activate multiple endogenous genes simultaneously in response to extracellular ligands.

The results showed that transitivity could be responsible of multiple endogenous genes knock-down.

Open image in new window Figure 2 Simultaneously transcriptional activation of multiple endogenous genes using either dLbCpf1-p300core or dLbCpf1-SunTag system with a single gRNA for each gene.

To study the transcriptional network in a systematic manner, regulating multiple endogenous genes is required, prompting the development of efficient technology for simultaneous regulation of multiple endogenous genes.

To what extent multiple endogenous genes could be regulated simultaneously has not been explored.

Recent studies have shown an advantage of using multiple endogenous control genes for the qPCR experiment [ 23], and therefore we used three endogenous control genes including β-2 microglobulin (B2M), glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and β-actin (ACTB) in the qPCR experiment.

The Scherf laboratory has recently generated a parasite mutant strain expressing multiple endogenous var genes simultaneously at the same spatial expression site (Q. Zhang and A. Scherf, unpubl. data).

Significantly, knockdown of Cdx4 led to marked reduction of multiple 5' Hoxa cluster genes, including Hoxa9 in AT1 cells (Fig. 4B), whereas ectopic expression of Cdx4 upregulates expression of multiple endogenous Hoxa cluster genes including Hoxa9.

In this work we made no effort to silence the multiple endogenous Wt-Ub genes.

Therefore, it may be necessary to target multiple cellular co-factors, including endogenous genes that are required for cell entry, integration, transcription, and maturation of the virus.