Sentence examples for multiple endogenous microbicides from inspiring English sources

An alternative explanation is that the anti-HIV activity of CVL stems from a combination of multiple endogenous microbicides and that the assessment of no single factor adequately captures the sum total anti-HIV activity of any one woman's CVL microbicides [15], [16], [48].

In this study, we assessed the levels of multiple candidate endogenous microbicides in cervicovaginal lavage (CVL) specimens from HIV and HIV women, and characterized whether these microbicides correlate with protection from HIV infection.

Coupling of dCas9 to a transcriptional repressor domain can robustly silence expression of multiple endogenous genes.

Diurnal control is mediated by multiple endogenous and exogenous mechanisms, even at the level of individual genes.

The CRISPR ChaCha is dose-dependent, reversible, and can activate multiple endogenous genes simultaneously in response to extracellular ligands.

It is therefore relatively simple to produce numerous sgRNAs to target multiple endogenous sequences.

The results showed that transitivity could be responsible of multiple endogenous genes knock-down.

A synthetic biomolecular circuit identifies abnormal cell states by the integration of multiple endogenous microRNA inputs.

These data suggest that HIV infection alters the distribution of some endogenous microbicides in FRT secretions.

Of the four microbicides analyzed, we found that the levels of two endogenous microbicides, HBD2 and MIP3α correlated with activity against HIV.

Yet, while considerable attention has been directed to developing topical exogenous microbicides that reduce transmission of HIV-1, relatively little is known about endogenous microbicides produced within the female reproductive tract (FRT).