Sentence examples for mouse neural precursor from inspiring English sources

Neurospheres, which are the most widely used form of culturing mouse neural precursor cells, have limitations because they are heterogeneous [7].

They report that the proneural basic helix-loop-helix protein Ngn1 binds to the promoter of miR-9 and induces its expression in mouse neural precursor cells.

Under oxidative stress, mouse neural precursor cells stop proliferating and differentiate into astroglial cells (rather than neurons) through a SirT1-dependent mechanism that relies on Hes1 modulation and direct silencing of the Mash1 promoter [ 20].

Based on different cellular dielectric properties, without cell-type specific markers, neurons and astrocytes differentiated from mouse neural precursor cells can be detected and isolated in microfluidic channels (500 μm in width and 50 μm in height) [ 15].

6 samples were derived from mouse embryonic stem cells (ESCs) (3 Tdg +/−, 3 Tdg −/− ), 6 samples were from mouse neural precursor cells (NPCs) (3 Tdg+/−, 3 Tdg−/−), and 6 samples were obtained from mouse embryonic fibroblasts (MEFs) (3 Tdg+/+, 3 Tdg−/−).

In other studies based on SDS/PAGE and immunoblotting, mouse neural precursor cells grown as neurospheres have been reported to secrete phosphacan and aggrecan into the medium, and genes for aggrecan, neurocan, brevican, phosphacan and tenascin-C could be amplified from mouse neurospheres by RT PCR (reverse transcription PCR; Kabos et al., 2004).

In contrast, MELK knockdown arrested proliferation of mouse neural precursors without causing a significant increase in cell death, at least in vitro.

They showed that low doses of ionizing radiation temporarily arrested the proliferation of mouse neural precursors derived from embryonic stem cells, while cells irradiated at high doses permanently lost their proliferation capability (Isono et al., 2012).

To test this hypothesis, human-specific LADs were searched, which were defined as human LAD sequences which are 1) conserved in the mouse and human genomes and 2) located outside of the LAD boundaries in the mouse genome of the four distinct types of murine cells, namely mouse ESCs, neural precursor cells, astrocytes, and mouse embryonic fibroblasts (Guelen et al. 2008; Peric-Hupkes et al. 2010).

When mouse-derived neural precursor cells are encapsulated in vitro in these gels, rapid and selective differentiation of the cells into neurons is observed [ 28].

From mouse NSCs and neural precursor cells, certain gangliosides other than GD3 such as GT1b, GQ1b, GT1aα [originally designated GTx (Nakamura et al., 1988); Chol-1α antigen] and GQ1bα (Chol-1α antigen) have been identified so far (Yanagisawa et al., 2004; Ngamukote et al., 2007; Nakatani et al., 2010; Yanagisawa, 2011).