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We next decided to use the immortalized mouse neural progenitor cell line C17.2 (ref. 26) for more detailed molecular studies.
Ishimoto, T. et al. Organic cation transporter-mediated ergothioneine uptake in mouse neural progenitor cells suppresses proliferation and promotes differentiation into neurons.
We examined the ability of the non-viral phiC31 integrase system to promote stable transgene expression in mouse neural progenitor cells (mNPCs).
Zhang Y, Dong Y, Zheng H, Shie V, Wang H, Busscher JJ, Yue Y, Xu Z, Xie Z. Sevoflurane inhibits neurogenesis and the Wnt-catenin signaling pathway in mouse neural progenitor cells.
Wnt3a has been shown to promote hippocampal neurogenesis by shortening the cell cycle duration of mouse neural progenitor cells [43].
Geminin is expressed in both embryonic and adult mouse neural progenitor cells, and in the Xenopus central nervous system throughout embryonic development [5], [6].
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Schwamborn, J. C., Berezikov, E. & Knoblich, J. A. The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors.
Here, we studied this process using transcriptome-wide single-cell RNA sequencing of mouse neural progenitors expressing the mesDA neuron determinant Lmx1a.
This has already been demonstrated using mouse neural progenitors which already express Sox2 [83], [83].
Other studies have shown that PDGF-A can bias cell-fate decisions, for example mouse neural progenitors residing in the SVZ are induced to become OPCs rather than neurons in response to PDGF treatment [31].
The deficiency was documented in mouse ES cells, mouse neural progenitors, and human CD34+ haematopoietic progenitors.
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