Sentence examples for mouse model specific from inspiring English sources

While in the mouse model, specific conditions can be studied in detail, clinical conditions are different.

In a SCA1 mouse model, specific genes involved in glutamate signaling functions were deregulated in Purkinje cells, one major target of the disease [14].

Genes module assignments, module membership and mouse model specific elements.

However, a similar study with genetically modified mouse models of PDA needs to be pursued in order to exclude the possibility, that the observed effects are mouse model specific.

Moreover, genetic downregulation of autophagy in an atg5flox/flox mouse model (specific deletion of Atg5 in RGCs) or in an atg4b−/− mouse model reduces the number of living cells after ONT.

In humans and mouse models, specific point mutations in nuclear lamins are the cause for autosomal Emery-Dreifuss muscular dystrophy [ 22, 23].

To determine mouse model-specific components, genes that significantly associated to the blue module in any, but not all of the mouse models were selected.

Mouse model-specific expression of several hub genes was confirmed using quantitative RT-PCR analysis of Ercc1 and App-Ps1 microglia.

Differential expression of several hub genes of the consensus blue module as well as mouse model-specific gene expression was validated using quantitative RT-PCR analysis of Ercc1 and App-Ps1 microglia.

Recently, a new mouse model for specific cyclooxygenase ablation, leaving peroxidase activity intact, has been generated [ 17], modeling the specific COX-2 inhibition of newer COX-2 inhibitors such as celecoxib and rofecoxib.

Using the APP-PS1-21 model model, also specific binding of [ 18 F]florbetapir was shown to increase from age 3 to 8 months; however, no further increase was detected at 12 months compared to the baseline scan at 3 months [11].