Sentence examples for mouse models specific from inspiring English sources

In humans and mouse models, specific point mutations in nuclear lamins are the cause for autosomal Emery-Dreifuss muscular dystrophy [ 22, 23].

While in the mouse model, specific conditions can be studied in detail, clinical conditions are different.

In a SCA1 mouse model, specific genes involved in glutamate signaling functions were deregulated in Purkinje cells, one major target of the disease [14].

Genes module assignments, module membership and mouse model specific elements.

However, a similar study with genetically modified mouse models of PDA needs to be pursued in order to exclude the possibility, that the observed effects are mouse model specific.

Moreover, genetic downregulation of autophagy in an atg5flox/flox mouse model (specific deletion of Atg5 in RGCs) or in an atg4b−/− mouse model reduces the number of living cells after ONT.

To determine mouse model-specific components, genes that significantly associated to the blue module in any, but not all of the mouse models were selected.

Mouse model-specific expression of several hub genes was confirmed using quantitative RT-PCR analysis of Ercc1 and App-Ps1 microglia.

Differential expression of several hub genes of the consensus blue module as well as mouse model-specific gene expression was validated using quantitative RT-PCR analysis of Ercc1 and App-Ps1 microglia.

Therefore we used a systematic approach to investigate the specific role of NPY signalling on bone homeostasis employing several NPY mutant mouse models including specific re-introduction of NPY into the hypothalamus of otherwise NPY deficient adult mice.

Similarly, when designing studies or developing genetically based mouse models of specific conditions, background genotypes and phenotypes may provide substantial advantage or disadvantage to achieving specific aims.