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In addition, this phenotype was observed in another transgenic mouse line expressing NANOS2-ZM (line #4), although expression of the transgene was restricted to a fraction of the male gonocytes in this line (supplementary material Fig. S1B D).

To further define the role of 5-HT1A receptor-expressing neurons, we generated a transgenic mouse line expressing Cre recombinase in these cells.

To investigate, we generated a transgenic wild-type mouse line expressing AQP1 in the fiber cells using αA-crystallin promoter.

A mouse line expressing mitochondrial Dendra2 (mito-Dendra2) has been generated to study mitochondrial dynamics in primary tissue (Pham et al. 2012).

In order to investigate the function of importin α7 in mice, we generated a knockout mouse line where importin α7 is completely deleted and a mouse line expressing a shortened form of importin α7 lacking the IBB domain.

This was achieved by mating homozygous mice carrying the loxP-flanked (floxed) S1P1 (S1P1fl/fl) [42] with a mouse line expressing Cre recombinase under the transcriptional control of the nociceptor-specific Nav1.8 gene (SNS-Cre) [43].

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A stable transgenic mouse line expressed 0.5 μg/ml of human G117H BChE in plasma as well as 2  μg/ml of wild-type mouse BChE.

The previously published DR4-H2E transgenic mouse line expresses a chimeric human-mouse MHC class II gene (HLA-DR4/H2Ed).

The MyoD-Cre mouse line expresses the Cre recombinase gene under the control of the MyoD promoter [ 12].

The TgOvPrP4 mouse line expresses the ovine prion protein gene (A136R154Q171 genotype) in a PrP null mouse background as previously described (25 ).

This mouse line expresses bovine PrPC (≈8× that of the level of PrPC in cattle brain) under the control of the mouse prnp gene promoter in a mouse PrP0/0 background (29 ).

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