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One of the most prominent phenotypes of both elg1 mutants and ctf4 mutants is their increased levels of recombination.
The two most prominent phenotypes in zebrafish are somitogenesis and pigmentation.
One of the most prominent phenotypes in masculinized females is the aberrant splicing of Bmdsx mRNAs.
Amongst the most prominent phenotypes associated with defective DSB repair in both humans and mice, is the onset of accelerated aging (progeria).
Surprisingly, after the first brain CK knockout transgenic mice became available, it took almost 10 years to figure out some of the most prominent phenotypes of this type of transgenic mice.
Defective morphogenesis of the anterior-posterior axis resulting in aberrant body curvature is one of the most prominent phenotypes in apc mcr/mcr zebrafish (Fig. 5) (Hurlstone et al., 2003).
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Accumulation in M-phase was the most prominent phenotype and notably, was also correlated with TP53 mutant status.
The most prominent phenotype noted by us and other investigators has been the surprising presence of a cleft palate in neonatal mice homozygous for null mutations in Gad1, Viaat and Gabrb3 [4], [5], [6], [6].
To exclude cardiac malfunction, the most prominent phenotype of Atgl−/− mice [12], Schoiswohl et al.
The most prominent phenotype in pnpla6 MO morphants is curly tail (Fig. 1A,B).
The most prominent phenotype resulting from vWF mutation is a severe bleeding tendency.
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