Strikingly, these changes are responsible for the most variable clinical phenotypes, ranging from asymptomatic to life-threatening conditions.
The heteroclite genes frequently displayed a relatively large number of genetic interactions because the deletion mutant genes conferred the most variable morphological phenotypes.
An increased variability of mRNA abundance in Pax6+/− lens originates most likely from variable phenotypes of individual mutant lenses [21], [23].
Clustering analysis using the 5,000 most variable probes highlighted relevant breast cancer phenotypes: ER+, PR+, HER2+ and triple-negative tumours.
The even-moment effect results from the fact that the fitness of individuals (or phenotypes) with the most variable fitness covary most strongly with w ¯ [ 32].
11 On the other hand, because of its complexity and patient exposure to a multitude of endogenous and exogenous factors, the pulmonary outcome is clinically the most variable as well as the most unpredictable component of the CF phenotype.
Within our most variable 2000 loci were probes for genes previously associated with a CIMP phenotype in GBM [ 10].
If we consider a mild scenario with a 3°C change affecting the most variable populations, the change in temperature would require a change in mean phenotype of 1.56 σp.
The most variable genes (∼3000 genes) were determined by their coefficient of variation, without reference to phenotype or gene function.
The vegetables are the most variable of variables, both in terms of kind and quantity.
