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However, some of the most interesting phenotypes are fixed in particular breeds and are therefore less tractable to genetic analysis using classical segregation-based mapping approaches.
Furthermore, widely used methods, based predominantly on alanine-scanning mutagenesis [ 56], are also limited in their capacity to uncover some of the most interesting phenotypes.
The pH dependence of the steady state kinetic constants was determined for 17X-PTDH-R301A and 17X-PTDH-R301K, the mutants with the most interesting phenotypes.
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Perhaps most interesting is the class 3 phenotype, which is barely distinguishable from knockdown of the Met receptor itself.
Among various phenotypes in Bst+/− mice, the most interesting are its retinal abnormalities, consisting of delayed closure of choroid fissures, decreased ganglion cells and subretinal vascularization.
Analyzing the data within the KEGG PATHWAYS and GO revealed several important pathways and functions reflecting the aggressive and resistant phenotype of mesothelioma and some of the novel and most interesting findings will be highlighted below.
One of the most interesting features of hexanucleotide repeat expansions of C9ORF72 is that the associated phenotype is extremely variable and indeed, except in certain pedigrees, the expansion does not appear to be 100%% penetrant [ 1].
The most interesting observation is, however, that the Cvi accession is unique for its big seed phenotype, which is seen when Cvi is the female parent.
Most interesting.
'Most interesting,' murmured Chan".
The most interesting find?
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