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Exact(6)
Polymorphism information content (PIC) ranged from 0.000 to 0.9159, with the most polymorphic markers being BMc238, BMc292, BMc321, BMc171, BMc367, BMc294 and BMc226, all di-nucleotide repeat based markers with PIC values above 0.8000.
Most polymorphic markers significantly associated with transcription were located in the compact region that was 380 680 bps upstream of the Lim3A major TSS, and were within binding sites for important transcriptional regulators.
Rather, most polymorphic markers that were significantly associated with transcript abundance seemed to be important in all tissues, and the exact significance level of the effect depended on the reliability of measurements in a particular tissue and on methods of analysis.
We found most polymorphic markers showed mainly two reproducible alleles in parent NL94.
Markers harboring multiple perfect microsatellites in their amplicon sequence (i.e., "multiple SSRs/amplicon") with 11-15 repeat units were the most polymorphic markers, followed by long dinucleotides and tetranucleotides with more than 11 repeat units.
Because the core collections were designed to maximize the genetic diversity and because SNPs for the 8k array were chosen among the most polymorphic markers in 27 dessert apple genomes (Chagne et al. 2012a), the allelic frequencies obtained may be biased compared to the full genetic pools of dessert and cider apples.
Similar(54)
Thus far, the gp60 gene is the most polymorphic marker identified in the Cryptosporidium genome.
The second method (Method B) makes use of the marker information at only the most polymorphic marker locus for individuals with an unknown linkage phase.
The average PIC value of the new polymorphic BMc markers was 0.310 and ranged from 0.099 for the least polymorphic markers to 0.657 for the most polymorphic marker (BMc70).
Microsatellite typing demonstrated that the isolates from each patient had evolved from a single original strain, because they were either identical at 6 markers or differed only in the most polymorphic marker.
In this study, about half of the tested markers were polymorphic in at least one of the five scallop species, with the most polymorphic marker transferable to up to four species, indicating the high cross-species transferability of the developed SNP markers.
Related(20)
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