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SE33 is one of the most informative markers in forensic use due to its high power of discrimination.
In many cases it is crucial to pick a minimal set of the most informative markers due to the limited amount of material available for analysis.
For CIM, 2 to 4 of the most informative markers per trait were chosen as cofactors.
The proliferation module classifier showed better sensitivity but lower specificity than the one based on statistically most informative markers.
Finally we use the designed QR algorithm [11] to select the first 100 less correlated markers among the initial top 500 most informative markers identified by PCA.
The rankings of the top most informative markers are quite stable as the tuning parameter varies, which may suffice for most applications.
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Locus INRA189 is the most informative marker with 10 alleles, differentiated among five Y1 and nine Y2 haplotypes.
In this setting, till the discovery of ERβ, ERα was the single most informative marker, receptor-negative tumors rarely benefiting from endocrine therapy [26] [27].
The method used for genotyping is well established in molecular epidemiological studies and the msp2 gene has proven to be the most informative marker of parasite population diversity [29].
Thus showing that the D3S1585 marker is the most informative marker.
This study also showed mammaglobin to be the most informative marker in their multimarker panel.
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