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Most polymorphic sites were single nucleotide polymorphisms (SNP; 174/179 variants), reflecting lower than average indel polymorphism [38].
In contrast, the evidence for strong LD surrounding the 7R allele is dramatic, with all 7R/7R individuals (including those from Africa) exhibiting the same alleles at most polymorphic sites.
Another difference observed between resistant and susceptible samples was that most polymorphic sites present only in resistant mosquitoes were heterozygotes suggesting that if a kdr mutation was present in this population, it may still be predominantly heterozygote.
Indeed, genotypes 3 and 4 were found here to have the higher fraction of variable sites in ORF1 and ORF2.N, even though most polymorphic sites were negatively selected.
The three pairs of fragments were amplified for the most polymorphic sites of the 86 individuals.
Most polymorphic sites did not occur at the functional conservative site, which ensures the α-amylase inhibitors maintain their ability to combine with α-amylase.
Similar(52)
Sensitivity of rat macrophages to pyroptosis in response to LT is directly linked to the presence of certain short amino acid sequences at the most polymorphic site within the N-terminal NR100 domain.
The approach was used to putatively identify the most divergent polymorphic sites within the transcriptome.
Given that singletons (i.e., sites with 1 or 10 individuals carrying the inferred derived state) are the most likely polymorphic sites to represent sequencing errors, the analyses were repeated excluding 5045 U→P and 14,912 P→U singletons.
Most A/T→G/C polymorphic sites reflect U→P changes in D. pseudoobscura yet the proportion of singletons is much lower for U→P sites (43.1%) than it is for P→U sites (60.7%; Figure 4).
Most of these polymorphic sites were single-base and scattered along a sequence.
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