Sentence examples for moieties of different from inspiring English sources

Here, we prepared compounds with acidic moieties of different pKa values to figure out that the hH3R tolerates these functionalities when added to a common pharmacophore blueprint.

It has been shown that polyethylene glycol moieties of different lengths improve pharmacokinetics of bombesin derivatives [20 23], although they may negatively affect affinity and internalization rates [23, 24].

Two dianhydrides, 3,3′,4,4'-diphenylsulfonetetracarboxylic dianhydride and 4,4'- hexafluoroisopropylidene diphthalic anhydride were selected as the electron acceptor considering their functional moieties of different charge-trapping depth and electron-withdrawing ability.

The design, synthesis and in vitro activities of a series of cinnamoyl nitrogen mustard pyrazole analogues of tallimustine 8 13, in which the amidino moiety has been replaced by moieties of different physico-chemical features are described, and the structure activity relationships are discussed.

The design, synthesis and in vitro activities of novel α-bromoacryloyl pyrazole, imidazole and benzoheterocyclic derivatives of distamycin A, in which the amidino moiety has been replaced by moieties of different physico-chemical features are described, and the structure activity relationships are discussed.

Although few general rules apply, Déziel et al. (1999, 2000) previously noted that for RL isomers containing two fatty acid moieties of different chain lengths, the predominant (at least twice more abundant) isomeric congeners will be those with the shorter chain adjacent to the sugar.

A comparative analysis was performed for compounds having the same length of fluorinated segment (F10) and variable length of the hydrogenated part (H6, H10, H12), and having identical hydrogenated segment (H12) connected to a fluorinated moiety of different lengths (F6, F8, F10).

For example, a detailed theoretical study was carried out by the cancer research institute of Philadelphia on the three-dimensional (3D) binding of carboxylate moieties to different metals [19].

The ability of recombinant α- l-fucosidase iso2 to catalyse transfer of α- l-fucosyl moiety to different types of acceptor molecules was studied.

To test the validity of this approach, we chose FΦR4 in the C-terminal ring as the CPP moiety and peptides of different lengths and charges (AAAAA, AAAAAAA, RARAR, and DADAD) as cargo (Table 1, compounds 13 16, respectively).

Although the oxLDL used to prepare oxLDL-IC was the same preparation as that of the free oxLDL, the trafficking of the lipid and protein moieties of oxLDL was different when the lipoprotein presented to cells free or as a part of an immune complex.